Database : HANSEN Search on : INFECCOES POR HIV [Subject descriptor] References found : 39 [refine] Displaying: 1 .. 20   in format [Detailed]

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Id: 19935 Author: Broek, Jacques van den; Chum, Hamza J; Swai, Ronald; O´Brien, Richard J. Title: Association between leprosy and HIV infection Tanzania. Source: Int. J. Lepr;65(2):203-210, Jun. 1997. tab, graf. Abstract: SETTING: An epidemiological study of the interaction of leprosy and HIV infection in Tanzania. OBJECTIVE: To establish the prevalence of HIV infection among leprosy patients, and to measure the association of HIV and leprosy by comparing the HIV prevalence in leprosy patients and blood donors. DESIGN: Testing for HIV infection in consecutively diagnosed leprosy patients (new and relapsed after MDT) in all regions in Tanzania successively for a period of 3 to 6 months during 1991, 1992 and 1993. RESULTS: Out of the total estimated eligible leprosy patients, 697 patients (69%) entered the final analysis. The HIV prevalence among these leprosy patients was 12% (83/697) as compared to 6% (8960/ 158,971) in blood donors examined in Tanzania during the same period. There were no significant differences in HIV seroprevalence by age, sex, residence or type of disease. However, the adjusted odds ratio (OR) of the presence of a BCG scar was 1.9 [95% confidence interval (CI) 1.1-3.3] among HIV-positive leprosy cases compared to HIV-negative leprosy cases. Comparing leprosy cases with blood donors as controls, the logistic regression model, controlling for sex, age group and residence, showed the OR for HIV seropositivity among leprosy patients to be 2.5 (95% CI 2.0-3.2). This association existed in all strata, but was strongest in the 15-34-year age group. No difference of HIV status between multibacillary and paucibacillary leprosy could be shown to exist. The point estimate of the population attributable risk of HIV infection for leprosy was 7%. CONCLUSION: HIV infection is associated with leprosy and might reverse the epidemiological trend of the slow decline in case notification in Tanzania if HIV infection is increasing greatly. Previous BCG vaccination loses its protection against leprosy in the presence of HIV infection. A repeated study is recommended in order to validate these findings, whereby recording of the disability grading of the cases is necessary to adjust for delay in diagnosis. (AU)^ien. Descriptors: Hanseníase/compl Hanseníase/epidemiol Anticorpos Anti-HIV/anal Infecções por HIV/compl Infecções por HIV/epidemiol Limits: Humanos Masculino Feminino Adolescente Adulto Location: BR191.1

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Id: 13938 Author: Dredge, Keith; Marriott, J. Blake; Dalgleish, Angus G Title: Immunological effects of thalidomide and its chemical and functional analogs ..- Source: s.l; s.n; 2002. 13 p. ilus, tab. Abstract: Thalidomide has recently shown considerable promise in the treatment of a number of conditions, such as leprosy and cancer. Its effectiveness in the clinic has been ascribed to wide-ranging properties, including anti-TNF-alpha, T-cell costimulatory and antiangiogenic activity. Novel compounds with improved immunomodulatory activity and side effect profiles are also being evaluated. These include selective cytokine inhibitory drugs (SelCIDs), with greatly improved TNF-alpha inhibitory activity, and immunomodulatory drugs (IMiDs) that are structural analogs of thalidomide, with improved properties. A third group recently identified within the SelCID group, with phosphodiesterase type 4-independent activity, is in the process of being characterized in laboratory studies. This review describes the emerging immunological properties of thalidomide, from a historical context to present-day clinical applications, most notably in multiple myeloma but also in other cancers, inflammatory disease, and HIV. We also describe the laboratory studies that have led to the characterization and development of SelCIDs and IMiDs into potentially clinically relevant drugs. Early trial data suggest that these novel immunomodulatory compounds may supercede thalidomide to become established therapies, particularly in certain cancers. Further evidence is required, however, to correlate the clinical efficacy of these compounds with their known immunomodulatory, antiangiogenic, and antitumor properties. (AU). Descriptors: TALIDOMIDA/analog TALIDOMIDA/imunol TALIDOMIDA/farmacol SISTEMA IMUNE/ef drogas NEOPLASIAS/quimioter NEOPLASIAS/imunol INFECCOES POR HIV/quimioter INFECCOES POR HIV/imunol ADJUVANTES IMUNOLOGICOS/farmacol INIBIDORES DE ANGIOGÊNESE/imunol INIBIDORES DE ANGIOGÊNESE/farmacol ANTIVIRAIS/imunol ANTIVIRAIS/farmacol Limits: HUMANO Electronic Medium: http://www.ilsl.br Location: BR191.1; 04731/s

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Id: 13734 Author: Lawn, S. D; Wood, C; Lockwood, D. N Title: Borderline tuberculoid leprosy: an immune reconstitution phenomenon in a human immunodeficiency virus-infected person ..- Source: s.l; s.n; 2003. 2 p. ilus. Abstract: Two months after starting highly active antiretroviral treatment (HAART), an individual with human immunodeficiency virus type 1 (HIV-1) infection and profound CD4+ T lymphocytopenia developed several erythematous plaques on his face, which were due to borderline tuberculoid leprosy with reversal reaction. The temporal association between the development of these lesions and changes in blood CD4+ lymphocyte count and plasma HIV-1 load observed during HAART strongly suggests that the presentation of leprosy resulted from immune reconstitution. (AU). Descriptors: INFECCOES OPORTUNISTAS RELACIONADAS COM A AIDS/imunol AGENTES ANTI-HIV/uso terap TERAPIA ANTI-RETROVIRAL DE ALTA ATIVIDADE/ef adv CONTAGEM DE LINFOCITO CD4 INFECCOES POR HIV/compl INFECCOES POR HIV/quimioter INFECCOES POR HIV/imunol HANSENIASE TUBERCULOIDE/etiol HANSENIASE TUBERCULOIDE/imunol IMUNIDADE/ef drogas Limits: RELATO DE CASO HUMANO MASCULINO ADULTO Electronic Medium: http://www.ilsl.br Location: BR191.1; 09026/s

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Id: 13651 Author: Lanjewar, D. N; Bhosale, Ashish; Iyer, Anita Title: Spectrum of dermatopathologic lesions associated with HIV/AIDS in India ..- Source: s.l; s.n; July 2002. 6 p. ilus, tab. Abstract: Histopatholgoical analysis of cutaneous lesions in 195 patients with HIV/AIDS was carried out between 1989 to 1997 at tertiary level public hospital in Mumbai. 104/195 (53 per cent) cases showed infectious diseases which comprised of molluscum contagiosum (28), condyloma accuminata (18), verruca vulgaris (7), varicella zoster (5), syphilis (14), tuberculosis (13), donovanosis (4), leprosy (2), chancroid (2), bacillary angiomatosis (2), lymphogranuloma venercum (1), Norwegian scabies (3), leishmaniasis (2), demodicidosis (1), crytococcosis (1), tinea versicolor (1). In 12 (6 per cent) cases neoplasms were observed which included squamous cell carcinoma (9), basal cell carcinoma (2) and kaposi's sarcoma (1) case. The miscellaneous conditions were observed in 66(33.5 per cent) cases which comprised of psoriasis (21), papular urticaria (13), Reiter's disease (7) and eosinophilic folliculitis (6). The prevalence of cutaneous tuberculosis observed in this study is high as compared with western literature while the prevalence of kaposis's sarcoma is quite low as compared with reports from Africa, USA and United Kingdom. (AU). Descriptors: SINDROME DE IMUNODEFICIÊNCIA ADQUIRIDA/compl INFECCOES POR HIV/compl INDIA/epidemiol PREVALÊNCIA DERMATOPATIAS/compl DERMATOPATIAS/epidemiol XERODERMA PIGMENTOSO/epidemiol XERODERMA PIGMENTOSO/etiol Limits: HUMANO Electronic Medium: http://www.ilsl.br Location: BR191.1; 09127/s

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Id: 13625 Author: Antunes, Abílio; Nina, Jaime; David, Suzana Title: Serological screening for tuberculosis in the community: an evaluation of the Mycodot procedure in an African population with high HIV-2 prevalence (Republic of Guinea-Bissau) ..- Source: s.l; s.n; 2002. 5 p. tab. Abstract: The immuno-dot-blot assay MycoDot, which detects lipoarabinomannan (LAM) antibodies, was evaluated for the serological diagnosis of active pulmonary tuberculosis in patients in a rural community in the Republic of Guinea-Bissau. Sera from 269 adults (age > 15) and 33 children (age < 5) were assayed for antibodies in a blind manner and the results compared to the clinical status of tuberculosis. The assay had a specificity and a sensitivity of 92.4 per cent and 63.0 per cent respectively, when applied to the adult population. In HIV-2 infected individuals (27/269), the specificity and sensitivity of the assay were similar, 94.7 per cent and 62.5 per cent respectively. The assay did not provide high sensitivity for the diagnosis of tuberculosis in children. Sera from patients with leprosy cross-reacted with the antigen of the assay. It is concluded that this easily performed assay may be useful for the presumptive diagnosis of tuberculosis in adult populations in rural areas of developing countries where routine screening is not readily available. (AU). Descriptors: ANTICORPOS ANTIBACTERIAS/sangue GUINE BISSAU INFECCOES POR HIV/compl HIV-2 IMMUNOBLOTTING/métodos LIPOPOLISSACARIDIOS/uso diag POPULACAO RURAL MYCOBACTERIUM TUBERCULOSIS/isol SENSIBILIDADE E ESPECIFICIDADE TUBERCULOSE/compl TUBERCULOSE/diag TUBERCULOSE/patol TUBERCULOSE/virol Limits: ESTUDO COMPARATIVO HUMANO PRÉ-ESCOLAR CRIANÇA ADULTO SUPPORT, NON-U.S. GOV'T ADOLESCENTE Electronic Medium: http://www.ilsl.br Location: BR191.1; 09016/s

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Id: 13623 Author: Belliappa, Alamengada D; Bhat, Ramesh M; Martis, Jacintha Title: Leprosy in type I reaction and diabetes mellitus in a patient with HIV infection ..- Source: s.l; s.n; 2002. 2 p. ilus. Abstract: A 24-year-old man was referred to our department with history of a pale red raised lesion over the right side of the face with impaired sensation of 3 months' duration. He also had generalized weakness and increased thirst for the past 1 month. He had been treated with multidrug therapy for leprosy for 3 months and oral prednisolone for 1 month by his general practitioner. He also presented with a history of multiple sexual exposures with commercial sex workers and an ulcer ovver the penis 2 years ago, which healed spontaneously. (AU). Descriptors: DIABETES MELLITUS/compl DIABETES MELLITUS/patol DIABETES MELLITUS/terap INFECCOES POR HIV/compl INFECCOES POR HIV/patol INFECCOES POR HIV/terap HANSENIASE DIMORFA/compl HANSENIASE DIMORFA/patol HANSENIASE DIMORFA/terap Limits: RELATO DE CASO HUMANO MASCULINO ADULTO Electronic Medium: http://www.ilsl.br Location: BR191.1; 09013/s

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Id: 13540 Author: Lawn, S. D; Wood, C; Lockwood, D. N Title: Borderline tuberculoid leprosy: an immune reconstitution phenomenon in a human immunodeficiency virus-infected person ..- Source: s.l; s.n; Jan. 2003. 3 p. ilus. Abstract: Two months after starting highly active antiretroviral treatment (HAART), an individual with human immunodeficiency virus type 1 (HIV-1) infection and profound CD4+ T lymphocytopenia developed several erythematous plaques on his face, which were due to borderline tuberculoid leprosy with reversal reaction. The temporal association between the development of these lesions and changes in blood CD4+ lymphocyte count and plasma HIV-1 load observed during HAART strongly suggests that the presentation of leprosy resulted from immune reconstitution. (AU). Descriptors: HANSENIASE TUBERCULOIDE/etiol HANSENIASE TUBERCULOIDE/imunol INFECCOES POR HIV/compl INFECCOES POR HIV/quimioter INFECCOES POR HIV/imunol CONTAGEM DE LINFOCITO CD4 INFECCOES OPORTUNISTAS RELACIONADAS COM A AIDS/imunol AGENTES ANTI-HIV/uso terap TERAPIA ANTI-RETROVIRAL DE ALTA ATIVIDADE/ef adv IMUNIDADE/ef drogas Limits: RELATO DE CASO HUMANO MASCULINO ADULTO Location: BR191.1; 09166/s

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Id: 12276 Author: Banta, H. David Title: Global issues on the agenda at the World Health Assembly ..- Source: s.l; s.n; July 2001. 2 p. . Descriptors: CRIANÇA NUTRIÇAO DA CRIANÇA COMÉRCIO PAISES EM DESENVOLVIMENTO INFECÇOES POR HIV POLITICA DE SANEAMENTO POLITICA DE SAUDE LEGISLAÇAO DE MEDICAMENTOS HANSENIASE FORMULAÇAO DE POLITICAS SAUDE MUNDIAL VEICULOS HOMEOPATICOS Location: BR191.1; 08628/s

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Id: 11823 Author: Banta, H. David Title: Global issues on the agenda at the World Health Assembly: discussion of HIV/AIDS, leprosy, access to drugs ..- Source: s.l; s.n; 2001. 8 p. . Descriptors: HANSENIASE INFECÇOES POR HIV POLITICA DE SAUDE LEGISLAÇAO DE MEDICAMENTOS VEICULOS HOMEOPATICOS FORMULAÇAO DE POLITICAS SAUDE MUNDIAL Location: BR191.1; 08563/s

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Id: 11746 Author: Nwosu, C. M; Nwosu, S. N. N; Okoye, K. C Title: Human immunodeficiency virus and treponema pallidum infections in Nigerian patients with leprosy ..- Source: s.l; s.n; 1994. 4 p. tab. Descriptors: HANSENIASE HANSENIASE HANSENIASE HANSENIASE INFECÇOES POR HIV INFECÇOES POR HIV INFECÇOES POR HIV INFECÇOES POR HIV ANTICORPOS ANTI-HIV NIGÉRIA COMPORTAMENTO SEXUAL SIFILIS SIFILIS SIFILIS Location: BR191.1; 08521/s

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Id: 11656 Author: Nwosu, C. M; Nowosu, S. N. N; Okoye, K. C Title: Human immunodeficiency virus and Treponema palladium infections in Nigerian patients with leprosy ..- Source: s.l; s.n; 1994. 4 p. tab. Descriptors: HANSENIASE HANSENIASE HANSENIASE HANSENIASE ANTICORPOS ANTI-HIV INFECÇOES POR HIV INFECÇOES POR HIV INFECÇOES POR HIV INFECÇOES POR HIV COMPORTAMENTO SEXUAL SIFILIS SIFILIS SIFILIS TREPONEMA PALLIDUM Location: BR191.1; 08455/s

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Id: 11331 Author: Sankaran, J. R Title: HIV infection and leprosy - an enigma ..- Source: s.l; s.n; 1995. 3 p. . Descriptors: HANSENIASE HANSENIASE HANSENIASE AFRICA INFECÇOES POR HIV INFECÇOES POR HIV INFECÇOES POR HIV HIV-1 HIV-2 PREVALENCIA INDIA Location: BR191.1; 07270/s

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Id: 11306 Author: Miller, Marilyn T; Stromland, Kerstin Title: Teratogen update: thalidomide: a review, with a focus on ocular findings and new potential uses ..- Source: s.l; s.n; 1999. 16 p. ilus, tab. Descriptors: ANORMALIDADES DO OLHO ANORMALIDADES DO OLHO INFECÇOES POR HIV HISTORIA DA MEDICINA DO SÉCULO 15 HISTORIA DA MEDICINA DO SÉCULO 20 RECÉM-NASCIDO HANSENIASE TROCA MATERNO-FETAL NEOVASCULARIZAÇAO PATOLOGICA GRAVIDEZ SUÉCIA TERATOGENIOS TERATOGENIOS TALIDOMIDA TALIDOMIDA Deformidades Congênitas dos Membros/CI/EP/HI Location: BR191.1; 07245/s

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Id: 10984 Author: Fonseca, Eduardo; Garcia-Silva, Jesus; del Pozo, Jesus; Yebra, Maria Teresa; Cuevas, Jesus; Contreras, Felix Title: Syphilis in an HIV infected patient misdiagnosed as leprosy ..- Source: s.l; s.n; 1999. 4 p. ilus. Descriptors: HANSENIASE INFECÇOES POR HIV INFECÇOES POR HIV DERMATOPATIAS SIFILIS Location: BR191.1; 07335/s

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Id: 10968 Author: Burns, S. M Title: HIV in leprosy patients ..- Source: s.l; s.n; 1999. 2 p. . Descriptors: WESTERN BLOTTING ELISA HIV INFECÇOES POR HIV INFECÇOES POR HIV HANSENIASE HANSENIASE SENSIBILIDADE E ESPECIFICIDADE Location: BR191.1; 07427/s

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Id: 10963 Author: Calabrese, Leonard; Fleischer, Alan B Title: Thalidomide: current and potential clinical applications ..- Source: s.l; s.n; 2000. 9 p. tab. Descriptors: HANSENIASE LEPROMATOSA LEPROSTATICOS LEPROSTATICOS LEPROSTATICOS ARTRITE REUMATOIDE SINDROME DE BEHCET AGENTES DERMATOLOGICOS AGENTES DERMATOLOGICOS AGENTES DERMATOLOGICOS ECTROMELIA ERITEMA NODOSO DOENÇA ENXERTO-HOSPEDEIRO INFECÇOES POR HIV IMUNOSSUPRESSORES IMUNOSSUPRESSORES IMUNOSSUPRESSORES LUPUS ERITEMATOSO CUTANEO NEOPLASIAS DOENÇAS DO SISTEMA NERVOSO PERIFÉRICO ESTOMATITE AFTOSA TERATOGENIOS TALIDOMIDA TALIDOMIDA TALIDOMIDA Location: BR191.1; 07430/s

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Id: 10349 Author: Jha, J; Arankalle, V. A; Banerjee, K Title: Hepatitis C virus RNA positivity among RIBA-3 indeterminates ..- Source: s.l; s.n; 1995. 2 p. tab. Descriptors: DOADORES DE SANGUE DOENÇA CRONICA ELISA INFECÇOES POR HIV INFECÇOES POR HIV PESSOAL DE SAUDE HEPATITE C HEPATITE C HEPATITE C HEPATITE C ANTICORPOS PRESENTES EM HEPATITE C IMMUNOBLOTTING HANSENIASE LEPROMATOSA HANSENIASE LEPROMATOSA HEPATOPATIAS HEPATOPATIAS TRIAGEM DE MASSA RNA VIRAL HEMODIALISE FATORES DE RISCO SENSIBILIDADE E ESPECIFICIDADE VIREMIA Limits: ESTUDO COMPARATIVO Location: BR191.1; 07201/s

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Id: 10330 Author: Lockwood, Diana N. J; Pasvol, Geoffrey Title: Recent advances in tropical medicine ..- Source: s.l; s.n; 1994. 4 p. ilus. Descriptors: INFECÇOES POR HIV LEISHMANIOSE HANSENIASE MALARIA ONCOCERCIASE MEDICINA TROPICAL TUBERCULOSE Location: BR191.1; 07181/s

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Id: 10317 Author: Creange, Alain Title: Neuropathies infectieuses ..- Source: s.l; s.n; 2000. 6 p. tab. Descriptors: ANTIVIRAIS INFECÇOES POR HIV HEPATITE C HOSPEDEIRO IMUNOCOMPROMETIDO HANSENIASE DOENÇA DE LYME DOENÇAS DO SISTEMA NERVOSO PERIFÉRICO DOENÇAS DO SISTEMA NERVOSO PERIFÉRICO Location: BR191.1; 07387/s

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Id: 10246 Author: Bwire, Robert; Kawuma, H. J. S Title: Type 1 reactions in leprosy, neuritis and steroid therapy: the impact of the human immunodeficiency virus ..- Source: s.l; s.n; 1994. 2 p. tab. Descriptors: INFECÇOES POR HIV INFECÇOES POR HIV HANSENIASE HANSENIASE NEURITE NEURITE ESTEROIDES ESTEROIDES Location: BR191.1; 06956/s

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